Jonny Lee Miller

役 Sherlock Holmes

Lucy Liu

役 Dr. Joan Watson

Jon Michael Hill

役 Detective Marcus Bell

Aidan Quinn

役 Capt. Thomas "Tommy" Gregson

John Noble

役 Morland Holmes

Nelsan Ellis

役 Shinwell Johnson

Desmond Harrington

役 Michael Rowan

James Frain

役 Odin Reichenbach