Dr. Robert Dalgety, a dedicated and brilliant general surgeon, and Dr. Bruce Kellerman, head of cardiothoracic surgery, are two renegade surgeons working together in a megasized, megafrugal, aging HMO. With the help of Dr. Quinn Joyner and Dr. Maggie Yang, they buck the system any way they can in pursuit of the care patients need and deserve. On the opposing team are Shelly Pangborn, the new hospital administrator, and assistant hospital administrator, Frank Coones. Together with Nurse "Doctor" Poole, they are more concerned with the bottom line than patients' health.