Linda Cardellini

as Lindsay Weir

John Francis Daley

as Sam Weir

James Franco

as Daniel Desario

Samm Levine

as Neil Schweiber

Jason Segel

as Nick Andopolis

Martin Starr

as Bill Haverchuck

Becky Ann Baker

as Jean Weir

Joe Flaherty

as Harold Weir

Busy Philipps

as Kim Kelly

Seth Rogen

as Ken Miller