Steve Buscemi

as Enoch "Nucky" Thompson

Shea Whigham

as Elias "Eli" Thompson

Kelly Macdonald

as Margaret Schroeder Thompson

Vincent Piazza

as Charles "Lucky" Luciano

Gretchen Mol

as Gillian Darmody

Paul Sparks

as Mieczyslaw "Mickey Doyle" Kuzik

Michael Shannon

as Nelson Van Alden / George Mueller

Stephen Graham

as Al Capone

Michael K. Williams

as Albert "Chalky" White

Anthony Laciura

as Eddie Kessler